Comments (2)
Hi Matt,
There are a number of places a gradient can be supplied. Were you thinking for the FIM calculation, for improving gradient based search algorithms or something else?
Andy
from poped.
Thanks Andy,
Possibly for both. rxode2
calculates these for nlmixr2
focei and I thought they would be useful in both FIM calculation. I didn't see a hook so I didn't know if this was possible.
I was thinking of taking a nlmixr-style model and translating it to PopED, and was wondering if this would be useful and speed up the computation or increase the accuracy. This is currently mostly a development idea, but something I think may be useful.
Matt
from poped.
Related Issues (20)
- unused argument in plot_model_prediction() HOT 2
- parallel computation for plot_efficiency_of_windows() HOT 4
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