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cancer-proteomics-compendium-n2002

We assembled a compendium dataset of mass-spectrometry-based proteomics data of 2002 primary tumors from 14 cancer types and 17 studies

cptac_grade-stage_correlates

metastasis-expression-compendium

We synthesized and collated transcriptomes of patient-derived xenografts and patient tumor metastases, these data collectively representing 38 studies and more than 3000 patients and 4000 tumors.

snv-expression_integration

We have developed a systematic analytical approach to integrate non-coding somatic Single Nucleotide Variants (SNVs) with the altered expression of nearby genes, whereby, utilizing public genomic datasets, we have cataloged hundreds of genes appearing deregulated in association with nearby SNVs.

sv-expression_integration

We have developed a systematic analytical approach to integrate SV breakpoint information with the altered expression of nearby genes, whereby, utilizing public genomic datasets, we have cataloged hundreds of genes appearing deregulated by rearrangement-mediated cis-regulatory alterations.

svexpress

SVExpress is a suite of computational tools (implemented in Excel VBA and R) that allows one to identify Structural Variant (SV) breakpoint-to-expression associations across a set of cancer samples profiled for both SVs and gene transcription.