If an input to a binding reaction contains the enabler, remove the corresponding input from the MF about pathways2go HOT 1 OPEN

For the STAT5A example:

This one shows how this is a bit more complex than just checking a flat list of complex components. One of the inputs is the complex to remove "ERBB4s80:p-Y694-STAT5A:CSN2 gene" R-HSA-8954223 because the reaction's enabler "STAT5A_HUMAN" R-HSA-507995 is contained many levels down within this complex:

• ERBB4s80:p-Y694-STAT5A:CSN2 gene
  • ERBB4s80:p-Y694-STAT5A
    • STAT5A homodimer
      • p-Y694-STAT5A (R-HSA-507995)

Note: I'm not really sure what's with the difference in labels "STAT5A_HUMAN" vs "p-Y694-STAT5A" but they are both for R-HSA-507995.

Recursive traversal of the complex component hierarchy to check this is pretty trivial but I just wanted to highlight that this will be needed.

from pathways2go.