Comments (1)
Hi Kui,
this is hard to answer without more context, especially without knowing the speed of your CPU and your hard drive (whether it is an SSD or an HDD).
But in general, you can expect the time to grow with the length of the protein and the MSA search taking up to a few hours with a slow disk / CPU.
For the actual folding (i.e. running the AlphaFold model), the disk speed doesn't matter anymore, what matters is whether you are using a GPU and its performance.
from alphafold.
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from alphafold.