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Name: xiaoyi
Type: User
Bio: I was one of them!
Name: xiaoyi
Type: User
Bio: I was one of them!
Here we developed a novel and simple computational method based on deep learning named SRHiC to enhance the resolution of Hi-C data. We verified SRHiC on Hi-C data in human cell line. We also evaluated the generalization power of SRHiC by enhancing Hi-C data resolution across different cell types in the same or different species. Results showed that SRHiC outperforms the state-of-the-art methods in accuracy of prediction.
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