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Institute of Medical Biometry's Projects

adoptr icon adoptr

Adaptive optimal two-stage designs for clinical trials made easy.

blindrecalc icon blindrecalc

Compute characteristics and plots for blinded sample size recalculation

descrtab2 icon descrtab2

This package provides functions to create descriptive statistics tables for continuous and categorical variables.

fisherboschloo icon fisherboschloo

Sample size calculation and determination of raised nominal level for the Fisher Boschloo test for superiority and non-inferiority trials

fixedtimeanalyzr icon fixedtimeanalyzr

This package implements several methods for comparing survival curves at a fixed point in time. The tests are Chi-Square-Tests that rely on test statistics developed by John P. Klein et al. in their article "Analyzing survival curves at a fixed point in time" published in Statistics in Medicine 26 (2007).

netmat icon netmat

This is an extension of Audrey Beliveau's BUGSnet package. We have extended the original package by a set of functions relating to mixed metaanalysis of aggregate and individual patient data. This extension encompasses all methods applied in Proctor et al. (2022).

onearmphasetwostudy icon onearmphasetwostudy

OneArmPhaseTwoStudy — Planing, Monitoring and Evaluating Oncological Phase 2 Studies

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