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Novoa Lab's Projects

basecalling_models icon basecalling_models

Benchmarked base calling models for nanopore sequencing providing super high accuracy and improved RNA modification detection

codonautocorrelation icon codonautocorrelation

Compute codon autocorrelation from fasta CDS sequences (Novoa et al., Mol Biol Evol 2019)

deeplexicon icon deeplexicon

Signal based nanopore RNA demultiplexing with convolutional neural networks (Smith*, Ersavas*, Ferguson* et al., Genome Research 2020)

deeptools icon deeptools

Tools to process and analyze deep sequencing data.

differr_nanopore_drs icon differr_nanopore_drs

Scripts for identifying sites with differential error rates in mapped nanopore DRS data

drs_chikv_analysis icon drs_chikv_analysis

Direct RNA sequencing (DRS) analysis included in article: N6-methyladenosine modification is not a general trait of viral RNA genomes

epinano icon epinano

Detection of RNA modifications from Oxford Nanopore direct RNA sequencing reads (Liu*, Begik* et al., Nature Comm 2019)

m6abasecaller icon m6abasecaller

An m6A-aware basecalling model to detect m6A modifications at single nucleotide resolution in individual reads (Cruciani, Delgado-Tejedor, Pryszcz et al., BioRxiv 2023)

masterofpores icon masterofpores

Nextflow pipeline for analysis of direct RNA Nanopore reads (Cozzuto et al., Front in Genet 2020)

modphred icon modphred

modPhred is a pipeline for detection of DNA/RNA modifications from raw ONT data

mpileup2stats icon mpileup2stats

From samtools mpileup to stats of coverage, ref_nuc, mismatches, deletions, insertions, RT-stops

nano-trnaseq icon nano-trnaseq

Quantitative analysis of native tRNA populations using direct RNA nanopore sequencing (Lucas*, Pryszcz* et al., Nat Biotech 2023)

nano3p_seq icon nano3p_seq

Nanopore 3' end-capture sequencing (Begik et al., bioRxiv 2021)

nanorms icon nanorms

Prediction of RNA modifications and their stoichiometry from per-read features: current intensity, dwell time and trace (Begik*, Lucas* et al., Nature Biotech 2021)

rnamodmachinery icon rnamodmachinery

Analyses from manuscript: Integrative analyses of the RNA modification machinery reveal tissue- and cancer-specific signatures (Begik et al. Genome Biology 2020).

rpl3l icon rpl3l

Scripts used to produce plots in the RPL3L manuscript

squigglekit icon squigglekit

SquiggleKit: A toolkit for manipulating nanopore signal data

tombo icon tombo

Tombo is a suite of tools primarily for the identification of modified nucleotides from raw nanopore sequencing data.

ubu icon ubu

UNC-Chapel Hill Bioinformatics Utilities

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