Name: Open Targets
Type: Organization
Bio: An innovative, multi-year, industry-academia partnership that generates research insights to support systematic drug target identification and prioritisation
Twitter: opentargets
Blog: https://opentargets.org/
Open Targets's Projects
Retrospective of drug approvals support
Code and documentation for baseline expression and specificity data.
Helper scripts to ensure that indexes queried by PIS have not changed.
mappings used by the open targets platform to integrate data sources
The OpenTargets drug datasets enriched with genetics data using structural information.
Docker container definition for helping on data synchronization tasks into the EBI FTP Service
Synchronise EBI LSF locations to Google Cloud Platform
script to convert phewascatalog database to JSONs, with ENSGIDs and EFO ids.
Utility to convert gxa hierarchy files to JSON
Open Targets Genetics GraphQL API
QC, spin VMs, load data into DBs, create LUTs and other fun backend stuff we need to do to spin https://genetics.opentargets.org
Colocalisation pipeline for Open Targets Genetics
Fine-mapping pipeline for Open Targets Genetics
GWAS gold standards repository
Open Targets Genetics input support project.
Locus-to-gene scoring pipeline
GOS is an automatic and unified place to perform a release of OT Genetics to the public
Analysis code for Open Targets Genetics publications
Workflows for processing summary statistics files for Open Targets Genetics
Harmonise GWAS summary statistics against a reference VCF
Variant to disease dataset workflows for Open Targets Genetics
Workflows to generate cis-regulatory datasets used for variant-to-gene (V2G) assignment in Open Targets Genetics
Workflow to produce variant index annotation for Open Targets Genetics
This repository hosts the code to adapt the genetics output data to their data and schema iterations
Open Targets python framework for post-GWAS analysis