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jykr avatar jykr commented on June 18, 2024

Seems to be related to numpy version (tensorflow/tensorflow#559), please reopen if the update does not resolve the issue (without modifying CRISPResso2Align.pyx)

from crispr-bean.

jykr avatar jykr commented on June 18, 2024

This error happens with unspecified bases in FASTQ, leading to alignment score over/underflow. Currently bean only supports A/C/T/G for bases. If you need to accommodate special bases, please edit output_path/.aln_mat.txt (

self.output_dir + "/.aln_mat.txt",
).

from crispr-bean.

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