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Yulin Lyu

Peking Union Medical College Hospital, Beijing, China 100730 | [email protected]


EDUCATION

Postdoc in Rheumatology Peking Union Medical College Hospital (2023-present)

Ph.D. in Bioinformatics Peking University (2018-2023)

Bachelor in Biological Sciences Peking University (2014-2018)


PUBLICATION

  • Wang G*, Wang Y*, Lyu Y*, He H*, Liuyang S*, Wang J*, Sun S*, Cheng L, Fu Y, Zhu J, Zhong X, Yang Z, Chen Q, Li C, Guan J, Deng H. Chemical-induced epigenome resetting for regeneration program activation in human cells. Cell Rep. 2023 Jun 27;42(6):112547. doi: 10.1016/j.celrep.2023.112547.

  • Liuyang S*, Wang G*, Wang Y*, He H*, Lyu Y*, Cheng L, Yang Z, Guan J, Fu Y, Zhu J, Zhong X, Sun S, Li C, Wang J, Deng H. Highly efficient and rapid generation of human pluripotent stem cells by chemical reprogramming. Cell Stem Cell. 2023 Apr 6;30(4):450-459.e9. doi: 10.1016/j.stem.2023.02.008.

  • Guan J*, Wang G*, Wang J*, Zhang Z*, Fu Y*, Cheng L*, Meng G*, Lyu Y*, Zhu J, Li Y, Wang Y, Liuyang S, Liu B, Yang Z, He H, Zhong X, Chen Q, Zhang X, Sun S, Lai W, Shi Y, Liu L, Wang L, Li C, Lu S, Deng H. Chemical reprogramming of human somatic cells to pluripotent stem cells. Nature. 2022 Apr 13. doi: 10.1038/s41586-022-04593-5.

  • Xu Y*, Zhao J*, Ren Y*, Wang X*, Lyu Y*, Xie B, Sun Y, Yuan X, Liu H, Yang W, Fu Y, Yu Y, Liu Y, Mu R, Li C, Xu J, Deng H. Derivation of totipotent-like stem cells with blastocyst-like structure forming potential. Cell Res 2022 May 4. doi: 10.1038/s41422-022-00668-0.

  • Liu B*, Chen S*, Xu Y*, Lyu Y*, Wang J, Du Y, Sun Y, Liu H, Zhou H, Lai W, Xue A, Yin M, Li C, Bai Y, Xu J, Deng H. Chemically defined and xeno-free culture condition for human extended pluripotent stem cells. Nat Commun. 2021 May 21;12(1):3017. doi: 10.1038/s41467-021-23320-8.

  • Qu M*, Xiong L*, Lyu Y*, Zhang X, Shen J, Guan J, Chai P, Lin Z, Nie B, Li C, Xu J, Deng H. Establishment of intestinal organoid cultures modeling injury-associated epithelial regeneration. Cell Res. 2021 Mar;31(3):259-271. doi: 10.1038/s41422-020-00453-x.

  • Wang Q*, Sun D*, Liang Z*, Wang J, Zhong X, Lyu Y, Cao J, Lin Z, Du Y, Miao Z, Lu S, Li C, Xu J, Shi Y, Deng H. Generation of human hepatocytes from extended pluripotent stem cells. Cell Res. 2020 Sep;30(9):810-813. doi: 10.1038/s41422-020-0293-x.

Yulin Lyu's Projects

azimuth icon azimuth

A Shiny web app for mapping datasets using Seurat v4

ggunchull icon ggunchull

A ggplot extension for drawing smooth non-convex circles around a set of points.

projectlsi icon projectlsi

Project bulk/single-cell RNA-seq data to given LSI space

scassist icon scassist

Assist in the analysis and visualization of single-cell data.

schcllite icon schcllite

A simplized version of R package scHCL, faster.

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