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tfwillems's Projects

cas12a icon cas12a

Scripts for: "Optimization of AsCas12a for combinatorial genetic screens in human cells"

downloadhgdp icon downloadhgdp

Simple repository to download and collate WGS data for several hundred HGDP samples from the ENA

emcontaminator icon emcontaminator

Infer contamination fraction in sequencing data using an EM algorithm

hipstr icon hipstr

Genotype and phase short tandem repeats using Illumina whole-genome sequencing data

mutea icon mutea

Python package to simulate and estimate Y-STR mutation models

pandera icon pandera

A light-weight, flexible, and expressive data validation library for dataframes

phasedbeagle icon phasedbeagle

Version of BEAGLE capable of outputting phased genotype probabilities

pysam-fix-type-hints icon pysam-fix-type-hints

Pysam is a Python module for reading and manipulating SAM/BAM/VCF/BCF files. It's a lightweight wrapper of the htslib C-API, the same one that powers samtools, bcftools, and tabix.

read-stitcher icon read-stitcher

Efficiently merge overlapping paired-end reads using suffix trees

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