Comments (6)
why not endocytosis()
instead of intake()
?
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from bep.
Do you think endocytosis would be more appropriate for extracellular -> cytoplasm, cell surface -> cytoplasm, or both?
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I think both extracellular and cell membrane to cytoplasm (see http://purl.obolibrary.org/obo/GO_0006897), but that could be challenging for BEL purposes since the translocation term should connect A[loc1] to A[loc2].
going with a more generic import()
(http://purl.obolibrary.org/obo/GO_0098657) would pose the same challenges, but would include the additional transport processes mentioned by @johnbachman .
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Perhaps this would warrant adding another field to the translocation()
function to specify how translocation was done? Otherwise writing a translocation from the outside/surface of a cell to the inside loses the information on how it was done, and make endocytosis, active transport, passive transport, etc. effectively the same
from bep.
- CTD uses "uptake" as a general term and "import" as a more specific term (see: http://ctdbase.org/help/glossary.jsp)
- GO uses import into cell with synonym "uptake"
Without being so specific as to describe the method by which a molecule/protein/etc. moves into a cell, I think this might be the best term
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Related Issues (19)
- Relocate BEP repository to https://github.com/openbel organization HOT 1
- Write BEP for equivalentTo relationship
- Write BEP for regular expression namespace definitions HOT 1
- Write BEP for gmod() function HOT 1
- Write BEP for special EvidenceType annotation HOT 9
- Compelling example for populationAbundance in complex HOT 2
- Add BEP for numeric annotations HOT 1
- Write BEL Style guide (BEP8)
- Schedule November 2018 BEP Review Meeting HOT 1
- BEP for specification of BEL version
- Write BEP for partOf relationship HOT 4
- BEL v2.1 Release Plan and Release Plan Plan
- BEL v2.1 Release
- How to encode domains in BEL HOT 5
- Adding new terms to BEL default namespace HOT 3
- Update openbel.org website HOT 3
- http://bel.bio/bep is down HOT 1
- Make BEL v2.2 medium post HOT 2
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