Comments (1)
Hi Juliette,
I'm glad you think CATCH could be useful!
I'm no longer updating the datasets included in CATCH and will deprecate that input method over the coming months. Instead, I think the better path forward is using the download:TAXID
method to specify input species; this will automatically fetch the latest genomes from NCBI for you when you run CATCH. This is described in the README here. It's similar to using the provided datasets (although does require you to curate a list of NCBI taxonomy IDs for the different species), except always up-to-date. It's also the method I've been using to design probe sets over the past year.
I'd also note that the V-All probe sets available here designed in late 2018 should still be useful for many broad applications, unless there are specific applications you have in mind that involve either novel viral species or subspecies (e.g., SARS-CoV-2) or viruses with high drift over time (e.g., influenza).
Let me know if you have any questions about this or how to use that method.
Hayden
from catch.
Related Issues (14)
- Incorrect fasta paths for some genomes in directories HOT 1
- Error running design.py HOT 2
- Cluster input sequences by producing signatures of them HOT 1
- Having trouble accessing preloaded datasets HOT 12
- Replicability Zika probes Metsky et al Nature Biotechnology HOT 3
- Issue running design.py on large files HOT 3
- clarification of -e and -m flag function HOT 2
- build from clustered segments results in probes w/ less than target coverage HOT 3
- identify conserved regions or regions suitable for differential identification, and design PCR primer HOT 2
- catch on large input HOT 4
- Error when running design.py example HOT 2
- Error using design.py HOT 2
- CATCH fails on macOS starting with Python 3.8
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