diptavo / multiskat Goto Github PK

Dear Diptavo,

I am interested in applying MultiSKAT genome-wide. I have genotypes from whole exome sequencing in Plink format and was looking into an equivalent to SKAT.SSD.All(), but could not find it. Does such a function exist in MultiSKAT or can you recommend an alternative how to run MultiSKAT genome-wide? Thanks!

Best,

Alex

Hi,

I just downloaded the zip file and got this error when running: R CMD INSTALL MultiSKAT-master.zip

Error in rawToChar(block[seq_len(ns)]) : 
  embedded nul in string: 'PK\003\004\n\0\0\0\0\0\xce>\x88K\0\0\0\0\0\0\0\0\0\0\0\0\021\0\t\0MultiSKAT-master/UT\005\0\001\xb4\xb5*ZPK\003\004\n\0\0\0\0\0\xce>\x88K_\x91\xc0\x84\t\0\0\0\t\0\0\0\033\0\t\0MultiSKAT-mast'

could it be an OS issue? I am currently using Ubuntu 14.04.

Thanks,
Kevin

Hi, thanks for providing Multi-SKAT package. I learned from the paper that this method was designed for continuous phenotypes. I'm wondering what's your opinion on using it on binary phenotypes? Is that an option for multi-skat currently? Thank you!