A systematic review and meta-analysis to ascertain the efficacy and safety of medical agents for idiopathic Parkinson syndrome to alleviate tremor specifically.

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Idiopathic Parkinson syndrome (iPS) is one of the most common neurodegenerative disorders characterised by the triad of bradykinesia, rigidity and tremor. Tremor at rest predominantly at one side is often perceived by patients as severely disabling and yet ranges among the most difficult symptoms to treat. In medically refractory cases, lesional approaches have proven to be effective alternatives. However, to date, there is no comprehensive analysis of non-surgical therapies to manage iPS-patients’ tremor. This repository summarises all steps of the data acquisition, extraction and analyses.

• R version 4.1.1
• Endnote X7
• MIcrosoft Excel 2019
• WebPlotDigitizer-4.4

Dr. David Pedrosa MD, PhD Senior consultant at the Department of Neurology, Head of the Movement Disorders Section, University Hospital Giessen and Marburg

Dr. Anna Pedrosa M.Sc. Palliative Care, Study Group Ethics in Medicine, Philipps-University Marburg, Marburg, Germany

Dr. Josefine Waldthaler MD, PhD Consultant at the Department of Neurology, Movement Disorders Section, University Hospital Giessen and Marburg

Dr. Felicitas Mügge, Resident at the Department of Neurology, Movement Disorders and Neuromodulation, University Hospital Giessen and Marburg

Prof. Lars Timmermann Chair of the Department of Neurology, University Hospital Giessen and Marburg

• https://bmjopen.bmj.com/content/11/8/e048367.abstract
• https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=202911
• https://www.uni-marburg.de/de/fb20/bereiche/kopfz/neurologie/forschung/agbun/

This project is licensed under the terms of the MIT license.