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nips-compbio-paper-2016's Introduction

nips-compbio-paper-2016

Here I am outlining the ideas for a potential workshop paper for NIPS 2016.

Paper ideas:

1st paper

  • compare FFN + index encoding vs. FFN(seq[:4] + seq[-4:]) vs. LSTM
  • the effect of learning rates on all these architectures

2nd paper

  • pimp LSTM so that it comes close to or outperforms FFNN.

3rd paper

  • apply LSTM to MHC class II prediction

Things to include in the paper(s)

  • a page of exposition on the data + problem
  • the challenge of reducing short sequences into fixed input size models
  • talk about how LSTM would be ideal, and why it is a candidate
  • the importance of the learning rate

Some random ideas:

  • view LSTM as encoding technique, get LSTM to mimick kmer_index_encoding() to get comparabale result, then tweak it to beat it.
  • add attentional gate to LSTM
  • consider deep LSTMs
  • check what is going on with forget, and input gate.

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