Download current source code for SRPRISM
$ git clone https://github.com/ncbi/SRPRISM

Do following:
$ cd SRPRISM/srprism

To enable support for NGS library, needed to access NCBI SRA archive directly,
please uncomment the following line in the beginning of the top level Makefile
# export USE_SRA = 1
This will trigger automatic download and compilation of the NGS library.
In order to use pre-installed NGS and VDB libraries, uncomment the following
lines in the top level Makefile and change them to point to the relevant paths
# export NGS_PATH =
# export VDB_PATH =

To build SRPRISM application, do
$ make

After successful build, srprism executable can be found in app/ subdirectory.

Please see srprism/README file for usage infromation and examples.