$ python artifical_variants.py --help
usage: artifical_variants.py [-h] [--vartype {SNV,INS,DEL}]
                             input_transcript chrom output_vcf ref

Run make artifical variants(SNVs/InDels)

positional arguments:
  input_transcript      Transcript file(ex, brca1.txt)
  chrom                 Chromosome number(ex, 17)
  output_vcf            Output vcf file (ex, brca1_artifical.vcf)
  ref                   Spliting FASTA file by chromosome

optional arguments:
 -h, --help            show this help message and exit
 --vartype {SNV,INS,DEL}
                      Type of variant (default: SNV)