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hummod-standalone's Introduction

HumMod Library/Standalone

Below addresses common license concerns. We make every effort to explicitly state what is authorized versus what is not authorized. There are, however, things that we inevitably miss. If you're use case is not explicitly covered in our terms, please contact HC Simulations, LLC via their customer support page. In general, HumMod is freely usable for personal, educational, and research purposes without modification of source, excluding XML descriptions, which are licensed under GPL 2.0. Any commercialization or modification beyond what is previously approved requires approval from HC Simulations, LLC and possible sublicense.

License Stuff

Who owns HumMod?

The University of Missippi Medical Center (UMMC) is the copyright holder of HumMod and its derivatives. UMMC exclusively licenses HumMod to HC Simulations, LLC.

What is the license?

XML descriptions are licensed under GPL 2.0. All other products, source, or derivatives thereof require the explicit license from HC Simulations, LLC for modification, integration, commercialization, and any works not listed. The executables included in downloads are intended for personal and educational use. These downloads are free distributable with the XML; however, any modification, commercializations, etc. require sublicense through HC Simulations, LLC. For license inquiries, please contact HC Simulations, LLC through the HumMod support site at https://hummod.uservoice.com/.

Who do I contact about licensing HumMod for use in a project?

HC Simulations, LLC is the exclusive licensee of HumMod. To inquire about sublicense, please contact HC Simulations, LLC through their customer support page.

Things you can do:

  • Use HumMod for personal education and experiments
  • Use HumMod for research, including validation and subsequent publication
  • Use HumMod to modify education in the classroom, e.g. lab exercises
  • Modify the XML for personal, educational, or research purposes
  • Sublicense from HC Simulations, LLC

Things you can't do:

  • Have access to source without prior, signed written approval from HC Simulations, LLC
  • Modify or reverse engineer HumMod or derivatives thereof
  • Commercialize HumMod or derivatives thereof without prior, signed written approval from HC Simulations, LLC
  • Utilize HumMod or derivatives thereof for any purpose other than explicitly approved without prior, signed written approval from HC Simulations, LLC

If your use case is not explicitly covered in these terms, please contact HC Simulations, LLC for further guidance.

hummod-standalone's People

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hummod-standalone's Issues

Clamping parameters

In using HumMod for education, it would be useful to have the ability to clamp parameters at any desired level, even if that wouldn’t be possible in the real word.

For example, it would be good for teaching if I could individually clamp variables such as heart rate, arterial blood pressure, cardiac output, PVR, plasma NE, GFR, arterial pH, arterial PO2 and PCO2, ECFV Na+ and K+, osmoles in the body compartments, blood volume, and tidal volume and breathing rate. In some cases, control of these variables can already be achieved in the present model, but the control can be complicated to achieve (especially for students). For example, it's easy to use the ventilator to control breathing, but achieving a desired arterial PO2 requires balancing inspired O2 with ventilation, and achieving a desired arterial pH requires balancing bicarb infusion with increased inspired CO2 (which of course changes a different variable, too). Heart rate can be set above the intrinsic rate using the pacemaker, but not below the intrinsic rate. Same with NE secretion.

I realize the list of variables to control could be quite long, especially because every user might have her/his own list. Therefore, would it be possible to modify the Data boxes in the Tech window such that any variable, integral and implicit could be set to a constant? Or maybe just allow the user to write a script that would define the variables to be constant?

CRH-ACTH Axis

It would be valuable to incorporate the ACTH axis into the model, especially cortisol concentration and its effect on plasma glucose. From a teaching standpoint, cort is the only major hormone other than calcitonin/PTH that isn't in the model.

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