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juliawiggeshoff avatar juliawiggeshoff commented on September 2, 2024 1

@maximus3219 I don't know if you are still interested but I had the same problem last week. I wrote a Python script to calculate VAF for indels and snvs from the somatic VCF files. I couldn't get it done with bcftools either, but here is the script. It calculates the VAF for each variant and includes this information for the normal and tumour samples in the final output vcf. Usage instructions are on the README.md

from strelka.

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