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faah-inhibitor's Introduction

Heta project GH Build Build and Share gh-pages sbml-viewer GitHub release GitHub license DOI:10.13140/RG.2.2.18935.06563

FAAH inhibitor

This is part of heta-lang project.

This is Quantitative Systems Pharmacology (QSP) modeling platform describing Fatty Acid Amide Hydrolase inhibition in human.

Model history

  • The human model of FAAH inhibition was developed by InSysBio and Pfizer in 2012 to support the analysis of clinical data on perspective pain killer PF‐04457845.
  • The model was published in CPT: Pharmacokinetics & Systems Pharmacology journal in 2014.
  • The SBML code of the model was published on BioModels Database in 2014 under CC0 license.
  • In January 2016 it was model of the month of BioModels Database
  • In 2019 the model was published on GitHub as QSP modeling platform in Heta notation.

Contributors

  • Evgeny Metelkin
  • Natalia Bagrova
  • Neil Benson
  • Oleg Demin
  • Piet van der Graaf

Copyright

(c) InSysBio 2019-2021

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