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d3e's Introduction

D3E: Discrete Distributional Differential Expression

About

D3E is a tool for identifying differentially-expressed genes, based on single-cell RNA-seq data. D3E consists of two modules: one for identifying differentially expressed (DE) genes, and one for fitting the parameters of a Poisson-Beta distribution. A web-version which can be used for small samples can be accessed at http://www.sanger.ac.uk/sanger/GeneRegulation_D3E/

Files

  • D3EUtil.py : a collection of methods for running the D3E analysis
  • D3ECmd.py : an actual D3E tool (requires D3EUtil.py for execution)
  • D3EWed.py : a light version of D3E, for running as a web-service (requires D3EUtil.py for execution)
  • D3EMakeControl : a script for making a control file for the analysis
  • D3EAnalyse : a script for filtering DE genes based on the result of control file analysis

Getting Started

Please visit our Wiki pages for User Guide and Example.

d3e's People

Contributors

jenzopr avatar mdelmans avatar

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