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hybrid-faz's Introduction

Hybrid-FAZ

We release Hybrid-FAZ Alzheimer's diagnosis code.

Contributors: Chae-yeon Lim, Kyungsu Kim

Detailed instructions for diagnosis Alzheimer's are as follows.


Implementation

Pytorch implementation based on radiomics multi-feature based machine learning using FAZ segmentation image

Using Paper Dataset

Proposed: Hybrid-FAZ/Holdout_proposed_AI/*

baseline: Hybrid-FAZ/Holdout_baseline_manual/*


Environments

Required libraries for training/inference are detailed in requirements.txt

pip install -r requirements.txt

FAZ Segmentation

Conducting training through nnUNet using a public data set

Public dataset: https://zenodo.org/record/5075563

AI-based segmentation result

100 100

1000 1000

1001 1001

1002 1002


Multi-feature diagnosis

Radiomics multi-feature based machine learning diagnosis

Baseline code: path/to/Hybrid-FAZ/FAZ_code/FAZ_Holdout_test_baseline.ipynb

Proposed code: path/to/Hybrid-FAZ/FAZ_code/FAZ_Holdout_test_propose.ipynb

Pseudo code

image

Diagnosis result in holdout test

Method Accuracy (%) Sensitivity (%) Specificity (%) AUC (%)
Baseline 47.5± 5.8% 31.7± 12.2% 76.2± 14.4% 58.5± 5.4%
Proposed 64.8± 4.3% 50.4± 3.4% 83.7± 6.3% 72.0± 4.8%

Acknowledgements

thanks to MIC-DKFZ for sharing the segmentation nnUNet code.

nnUNet github: https://github.com/MIC-DKFZ/nnUNet

hybrid-faz's People

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