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ndar-stratification's Introduction

ASD adaptive behavior subtypes from NDAR dataset

We present here how to run the code to enable the stratification of Vineland scores from the NDAR database.

Requirements

Python >3.6

Install libraries with:

pip install -r requirements.txt

utils.py file

Create an utils file including variables as reported in example_utils.py

Pipeline

  1. Once the utils.py file is ready, run dataset method from create_dataset to obtain the long-format Vineland dataset and the dictionary of demographic information for each selected subject saved as namedtuple.

    Preprocessing steps include:

    Phenotype selection (import_data:_select_phenotype);

    Read tables from multiple instrument datasets (import_data:ReadData:data_wrangling);

    Merging of different instrument versions (e.g., renaming feature names) with create_levels:vineland_levels;

  2. Run the create_dataset:prepare_imputation function that drops subjects that have a percentage of missing information greater than the desired threshold.

  3. Grid search the best parameters for the Relative Clustering Validation. Considered different missing percentages thresholds and varying number of neighbors.

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