A Boolean network model to predict the phenotype of a biological network. The reference to this work is here:

Shen, L., Chepelev, I., Liu, J. and Wang, W. (2010) Prediction of quantitative phenotypes based on genetic networks: a case study in yeast sporulation, BMC Systems Biology, 4, 128.

There is also a follow-up study on this work based on the same idea:

Ding, S., & Wang, W. (2011). Recipes and mechanisms of cellular reprogramming: a case study on budding yeast Saccharomyces cerevisiae. BMC systems biology, 5(1), 50.