Comments (1)
lpantano
commented on June 3, 2024
Hi,
It is indeed a complex discussion. Without knowing your groups for your example I don't know if I would be able to help a lot.
I had one study that was disease across stages, being 0 the less aggressive state and 4 the most. When I did the clustering I had a bunch of groups that were all going UP across stages, with a little difference on saturating at 3 or 4. I did enrichment analysis for each of the group and I figured that those groups belonged to the same pathways, so I decided to merge it.
I would say you are looking for the biggest difference among your groups.
I hope this helps.
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