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The SPICE DAS client

A legacy repository of the SPICE DAS client (see reference).

A screenshot of SPICE

The Distributed Annotation System (DAS) defines a communication protocol used to exchange biological annotations. It is motivated by the idea that annotations should not be provided by single centralized databases, but instead be spread over multiple sites. Data distribution, performed by DAS servers, is separated from visualization, which is done by DAS clients. The original DAS protocol was designed to serve annotation of genomic sequences. We have extended the protocol to be applicable to macromolecular structures. This project contains the source code for SPICE, a DAS client that can be used to visualize protein sequence and structure annotations.

##References

Integrating sequence and structural biology with DAS.
Prlić A, Down TA, Kulesha E, Finn RD, Kähäri A and Hubbard TJ
BMC Bioinformatics 2007;8;333
PUBMED: 17850653; PMC: 2031907; DOI: 10.1186/1471-2105-8-333

Adding some SPICE to DAS.
Prlić A, Down TA and Hubbard TJ
Bioinformatics (Oxford, England) 2005;21 Suppl 2;ii40-1
PUBMED: 16204122; PMC: 2656757; DOI: 10.1093/bioinformatics/bti1106

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