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biogram's Introduction

Hi! My name is Michał Burdukiewicz and I am passionate about bioinformatics and R.

I am currently leading the Laboratory of Bioinformatics and Multi-omics Analysis at the Medical University of Białystok. Contact me if you want to collaborate with us!

My current projects:

I am also maintaining the list of machine learning models for prediction of peptide properties (see also our article on that).

I ❤️ R!

biogram's People

Contributors

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biogram's Issues

merging in calc_ed

calc_ed gives too large distances, when the merge inflates number of moves between groups. See

l2 <- list('1' = c("a", "b", "c"),
'2' = c("d", "e", "f"))

l3 <- list('1' = c("a", "b"),
'2' = c("d", "e"),
'3' = "c",
'4' = "f")

calc_ed(l2, l3)

Should be 2, is 3.

improve decode_ngrams

decode_ngrams should have also list of vectors output (in addition to the vector of pasted together sequences)

add utility functions: binarize and list2matrix

binarize:

ngram_matrix <- as.matrix(ngram_matrix)
ngram_matrix <- ngram_matrix > 0
storage.mode(ngram_matrix) <- "integer"

list2matrix

seqs_m <- tolower(t(sapply(seqs_list, function(i)
c(i, rep(NA, max(lengths(seqs_list)) - length(i))))))

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