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coatran's Introduction

My name is (Alexander) Niema Moshiri, and I am an Associate Teaching Professor in the Computer Science & Engineering Department at the University of California, San Diego. I work on computational biology, with a research focus on viral phylogenetics and epidemiology. I also place a heavy emphasis on teaching, namely on the development of online educational content, primarily Massive Adaptive Interactive Texts (MAITs). You can find more information about me on my website or in my Curriculum Vitae (CV).

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coatran's Issues

Allow user-specified RNG seed

Perhaps restructure code to seed the RNG in main(). If the user specifies a seed, use that to seed the RNG; if not, use system time

Usage of coatran_constant

Hello,

I am trying to run CoaTrans in the example files, and I do the following:
../coatran_constant big_transmissions.tsv big_times.tsv 1

But my output is only
(80296|CNG0-COM12-1399|0.821187:0.821187):0.000000;

So, I am wandering whether it is because there are more than one tree per transmission chain, the program is not outputting all the trees?
I am using a MAC OS Big Sur version 11.6.7

Thanks,
Fabricia.

Implement "transmission tree" and "infection time" versions of CoaTran

"Transmission Tree" will coalesce at the latest time possible (forward in time), meaning each coalescence will happen at the time of transmission. This is equivalent to using a constant effective population size of 0.

"Infection Time" will coalesce at the earliest time possible (forward in time, meaning each coalescence will happen at the time of infection. This is equivalent to using a constant effective population size of infinity.

I've laid out the relevant details in the Makefile and .gitignore; I just need to actually implement.

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