For this project, I developed an R Shiny application to examine a gene expression dataset comprised of RNASeq data from 20 individuals with Huntington's disease and 49 control samples. This dataset can be accessed on GEO (GSE64810) or downloaded from the data directory in this repo.

Ruifei Zhu

Final App - app.R final shiny app; functions.R all functions that will be sourced in app.R

Labadorf A, Hoss AG, Lagomarsino V, et al. RNA Sequence Analysis of Human Huntington Disease Brain Reveals an Extensive Increase in Inflammatory and Developmental Gene Expression [published correction appears in PLoS One. 2016;11(7):e0160295]. PLoS One. 2015;10(12):e0143563. Published 2015 Dec 4. doi:10.1371/journal.pone.0143563