用于储存病毒系统发育树相关的代码和数据

GISAID: Global Initiative on Sharing Avian Influenza Database

NCBI: National Center for Biotechnology Information

National Microbiological Data Center (accession number NMDC10013002 and genome accession numbers NMDC60013002-01 to NMDC60013002-10)

China National GeneBank (accession numbers CNA0007332–35)

BLAST

Lasergene 7.0

MEGA 6.0

PHYLIP

BEAST

FUBAR: fast-unconstrained Bayesian approximation

建议包含蝙蝠、猪、穿山甲、水貂、猴子源的冠状病毒,建议包含人工合成的 SHC014 重组病毒全基因组序列

• 全基因组比对
• 同源基因比对
• 非编码区域比对

• 最大简约法(Maximum Parsimony, MP)
• 最大似然法(Maximum Likelihood, ML）
• 贝叶斯推断法(Bayesian Inference, BI)

1. The 2019-new coronavirus epidemic: evidence for virus evolution
2. Evolution and variation of 2019-novel coronavirus
3. Discovery of a rich gene pool of bat SARS-related coronaviruses provides new insights into the origin of SARS coronavirus
4. Genomic characterisation and epidemiology of 2019 novel coronavirus: Implications for virus origins and receptor binding
5. Discovery of a novel coronavirus associated with the recent pneumonia outbreak in humans and its potential bat origin

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