This Pyhton 3.5 program is a real-time implementation of simultaneous 4 string guitar simulation with the algorithm of Karplus Strong.
This program uses PyAudio lib and NumPy.
In Windows I used the Anaconda 3.5 distribution, see PyAudio page to learn how to install PyAudio.
For Karplus-Strong details see the paper: Digital Synthesis of Plucked-String and Drum Timbres by Kevin Karplus and Alex Strong
MIT license.