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skovaka avatar skovaka commented on August 16, 2024 1

Your specs should be sufficient, although more CPU power might improve the level of enrichment. Performance is really sample- and flowcell-dependent, so it's hard to predict how many cores would be ideal. In general more is better, but running with 8 threads on 4 cores should work fairly well. I'd also make sure you have at least 500GB of free disk space for your run.

from uncalled.

snystrom avatar snystrom commented on August 16, 2024 1

Got it. Thanks for the help!

At the very least, I'll go ahead an express interest in supporting r10 pores if it helps convince someone to fund the work! 😄

from uncalled.

snystrom avatar snystrom commented on August 16, 2024

Great, thanks!

Performance is really sample- and flowcell-dependent

I did have another question related to this. Is there a reason this won't work for r10 flowcells? Or is it just untested? Are there plans to support them moving forward?

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skovaka avatar skovaka commented on August 16, 2024

r10 flowcells have very different signal characteristics than r9.4. The biggest challenge is that r10 pores cover more bases than r9.4, meaning our pore model would probably need longer k-mers, and it would take some work to efficiently handle that. We may work on it someday, but don't have any immediate plans.

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