Comments (3)
hrp1000
commented on July 19, 2024
1
Hi
As far as I know (but I could be wrong), there is no funding for this project and there is no-one working on it - last update to the code appears to have been early last year (2022). As a result, I think you could be waiting a long time for an update to the databases; this is a huge problem for all of us who are using the HH-Suite software.
One thing occurs to me - the folk at Deep Mind say that they used HHBlits as part of their work on AlphaFold, and they might have access to resources that could be used to fund this work. Just a thought (maybe they read things here...).
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milot-mirdita
commented on July 19, 2024
1
The MPI Toolkit team is building new databases. They are available here:
http://ftp.tuebingen.mpg.de/pub/protevo/toolkit/databases/hhsuite_dbs/
They are also linked in the README and in the download server page.
Additionally we built a new PDB100 with Foldseek instead of HHblits for ColabFold, but it should work without issues with HHblits/HHsearch: https://colabfold.mmseqs.com
We will continue to maintain the PDB100 HHblits database for ColabFold for now.
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hrp1000
commented on July 19, 2024
1
This is excellent news - but it shouldn't have taken a prod from me to reply to the OP!
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Related Issues (20)
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