Website project created following a Model–View–Controller (MVC) software design pattern in .NET Core framework. The output of this project contains the website for the Ryten Laboratory team. It also contains the specification for the RytenLab .NET Core REST API.

The major focus of the Ryten Laboratory is the use of transcriptomic data as a functional read-out of the genome and how that read-out can inform our understanding of biological processes to improve human health. We work in neurogenetics, one of the most challenging disease areas and use transcriptomic data, primarily derived from human brain or brain relevant cell types, to build the resources required to improve the molecular understanding of complex and rare neurological diseases with a particular focus on neurodegenerative diseases.

We are highly collaborative and we are interested in making our work accessible and useful within the neuroscience research community, but also within clinical and diagnostic settings. As part of UCL Great Ormond Street Institute of Child Health (London), and in collaboration with UCL Queen Square Institute of Neurology and University of Murcia (Spain), our on-going work covers the genetic regulation of gene expression in human brain, gene co-expression networks, re-annotation of genes associated with neurological diseases and the use of transcriptomics to improve diagnostic yield. We have released many of the outputs of these projects through the development of different web tools.

To find out more about our work and the people behind it just take a look at our Team webpage.

• .NET Core - The web framework used.
• MVC - The design pattern used.
• Apache HTTP Server Project - The webserver chosen to deploy the website.
• Kestrel - Web server natively used by .NET Core web applications.

• JQuery - A JavaScript library.
• Bootstrap - Front-end framework.
• Font Awesome - Icons used in the website.

Sonia García-Ruiz - Website UI developer.

Get in touch with Sonia at [email protected].

• All RytenLab members.
• University of Murcia.
• University College of London.