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hse22_project_minor

Ссылка на colab

https://colab.research.google.com/drive/1rkh9LTjdhWXzfEFQ9a0T_ZY32Cw93OEA?usp=sharing

Геномы и Z-DNA

Образец Кол. последовательностей Длина генома Кол. генов Доля генов Кол. Z-dna>500 Общая длина Z-dna>500
Cellulomonas fimi ATCC 484 1 4266344 3871 0.90158553 36858 484888
Cellulomonas flavigena DSM 20109 1 4123179 3760 0.90175663 35484 467186
Cellulomonas gilvus ATCC 13127 1 3526441 3248 0.91277438 33080 446507
Cellulomonas iranensis 1 4046676 3638 0.89839636 43205 588917
Cellulomonas shaoxiangyii 1 3909366 3504 0.9004941 35658 479625

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Кластеры и Z-DNA

Всего выявлено 3637 кластеров.

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Были выбраны следующие из них:

Кластер Кол. генов Функция ср. знач. Z-DNA score
1990 7 thioredoxin-disulfide reductase activity 10331
1461 8 ATP-binding 8005
1843 7 gluconokinase, Carbohydrate transport and metabolism 8831
127 7 ABC transporter ATP-binding protein 10295
2143 7 ABC transporter ATP-binding protein 20922

Выравнивание производилось с помощью MUSCLE 3.8:

Кластер 1990: Alt text

Кластер 1461: Alt text

Кластер 1843: Alt text

Кластер 127: Alt text

Кластер 2143: Alt text

Визуализация расположения Z-DNA относительно генов:

Кластер 1990: Alt text

Кластер 1461: Alt text

Кластер 1843: Alt text

Кластер 127: Alt text

Кластер 2143: Alt text

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