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biocintro's Introduction

Using R and Bioconductor to tackle bioinformatic challenges in epigenomics

September 18, 2018
Buffalo Niagra Medical Campus
Martin Morgan

This workshop provides an introduction to R / Bioconductor, motivated by epigenomic use cases.

Participants should have some experience using R, including use of RStudio. Participants should come with a laptop with WiFi access. Participants should be familiar with scientific concepts in epigenomics, including a basic understanding how methylation arrays and ChIP-seq experiments can inform biological insight.

The workshop will start with an overall orientation to Bioconductor software and annotation resources. We'll then explore typical steps in a Bioconductor workflow for analysis of methylation arrays using the minfi package, and similar steps in the analysis of ChIP-seq data using the csaw package. We place results from these workflows into biological context using Bioconductor annotation resources, and conclude with mention of advanced and emerging areas of Bioconductor relevance.

Time Topic
1:00 - 1:15 Introduction and Overview
1:15 - 2:00 Bioconductor packages, vignettes, and workflows
2:00 - 3:00 Methylation Arrays
3:00 - 3:15 Break
3:15 - 4:00 ChIP-seq Analysis
4:00 - 4:45 Results in Context
4:45 - 5:00 Advanced and Emerging Topics

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