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kdpp's Introduction

kdpp

k-DPP for subset selection using VLMC distances

This repository contains an example on how to use DPPy and Tensorflow to sample exactly from k-DPP and evaluate log probability. We use Nextflow to implement a pipeline to compute VLMC pairwise distances between sequencing reads. To use the Nextflow pipeline, you have to install the VLMC library dvstar.

Input: Pairwise distances between VLMC

Output: Samples from k-DPP

Requirement

  • Nextflow
  • BBTools such as bbduk.sh and reformat.sh
  • dvstar to generate pairwise distances between VLMC
  • DPPy
  • Tensorflow

TODO

Improve conversion from distance to similarity and implement Gibbs sampling.

Acknowledgement

Alexander Schliep, Joel Gustafsson for help with dvstar

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