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Description of work done at Merck pharmaceutical company in the summer of 2018 as a Computational Drug Discovery Intern at West Point, PA. Information excludes all proprietary information belonging to Merck & Co.

Home Page: https://www.merck.com/research/mrl-labs.html

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python lc-ms proteomics computational-proteomics swissprot pharmaceuticals pharmacokinetics pharmacodynamics research drug-discovery drug-targets computer-science scalable-data-analysis high-performance xml labkey drug-development numpy tkinter-python publication

computational-drug-discovery-internship-at-merck's Introduction

Bioinformatics Internship at Merck

Merck logo

Introduction

๐Ÿ“ฐ As of January 2019, a publication is underway related to the Automation of the Liquid Chromatography-Mass Spectrometry (LC-MS) Workflow Using a Run Sequence Wizard.

๐Ÿ“Œ This repository contains documents related to the work done at Merck pharmaceutical company in the summer of 2018 as a Bioinformatics Intern at West Point, PA. โ›”๏ธ Information excludes all proprietary information belonging to Merck & Co. โ›”๏ธ

๐Ÿ“Œ I specifically worked in the Merck Research Laboratories (MRL) โ–ถ๏ธ Pharmacokinetics, Pharmacodynamics and Drug Metabolism (PPDM) โ–ถ๏ธ Discovery Bioanalytical (DBA) group.

๐Ÿ“Œ During my WONDERFUL time there in the summer, I was involved with two projects which are explained in PDF documents in this repository. A brief explanation of each PDF document is provided below. I also was able to learn and experience first-hand the process of pharmaceutical drug development.

Files

๐Ÿ“œMain Project/ Automation of the Liquid Chromatography-Mass Spectrometry (LC-MS) Workflow Using a Run Sequence Wizard.pdf

This is the explanation of the main project I did over the summer at Merck in a โ— VERY DETAILED โ— manner. The beginning of the document has some main points for those that do not want to read through the whole document.

๐Ÿ“œSide Project/ Protein Drug-Target Scoring Python Script.pdf

Side project undertaken during Bioinformatics Internship at Merck that โ— led to novel drug targets that Merck is currently studying for creation of new therapeutics. โ—

๐Ÿ“œTalks and Posters/ Merck Research Symposium.pdf

Explanation of event and effects of my poster that occured at annual research symposium at Merck to which I was invited.

๐Ÿ“œTalks and Posters/ Invited Talk.pdf

Explanation of talk that I gave to a specific Merck department which occured after I was invited by the director of the department along with an upper-level scientist since they felt my work could have a direct impact on their department.

Contact Information

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Yogindra Raghav (YogiOnBioinformatics)

[email protected]

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