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ay-lab avatar ay-lab commented on July 26, 2024

Others have experienced similar problems if you look at the previous posts. It is likely because you have a scaffold or a chromosome that has all its fragments with bias values outside the range. Maybe we should put a specific warning for this. Just check to see which are scaffolds with bias values all less than 0.5 or above 2. Also, seems like your bias values are quite off in general, their average should be 1, yours are very small. Make sure to rescale them if this is the case.

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sunthink avatar sunthink commented on July 26, 2024

Thanks for your reply.

After removing these short length scaffolds with bias values all less than 0.5, fit-hic2 works.

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41622236 avatar 41622236 commented on July 26, 2024

Hi,everyone!
I also encountered this problem. But I still don't know how to solve it, can anyone help me ?

Thanks!

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