AACon is a set of tools implementing 17 different conservation scores reviewed by Valdar as well as the more complex SMERFS algorithm for predicting protein functional sites.
AACon is available as a SOAP web service, a stand alone Java executable and a Java library with concise API for accessing all the conservation methods programmatically. The executable runs on all platforms that support Java version 5 and above (Windows, Unix/Linux, Mac).
Downloads and more information how to use AACon at http://www.compbio.dundee.ac.uk/aacon/
Full documentation pages at http://www.compbio.dundee.ac.uk/aacon/docs/index.html
Issue Tracker: https://github.com/bartongroup/aacon/issues
Agnieszka Golicz, Peter V. Troshin, Fábio Madeira, David M. A. Martin, James B. Procter and Geoffrey J. Barton (2018) AACon: A Fast Amino Acid Conservation Calculation Service Submitted paper.
If you have any issues, questions or suggestions feel free to contact us on [email protected]