R-code for SNP-based heritability analyses. The methodology is an extension of brielin/Popcorn
- by incorporating the dependence of per-SNP heritability on allele frequency and LD-related functional annotations
- to use t-distribution for modeling allele substitution effect of SNPs
Run popcorn_example.R
Please cite: Takeuchi et al. Interethnic analyses of blood pressure loci in populations of East Asian and European descent. Nature Communications (2018) 9:5052 https://www.nature.com/articles/s41467-018-07345-0