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jardplard avatar jardplard commented on August 19, 2024

A quick update on the situation: based on the responses in the linked GitHub issue, I used the patched version of GenomeInfoDb and received a different set of errors+warnings.

Calling toGRanges() produces no errors, but the following warning: cannot switch some of GRCm38's seqlevels from NCBI to UCSC style. If this annotation data is used with annotatePeakInBatch(), this warning appears: not all the seqnames of myPeakList is in the AnnotationData.The 2 combined objects have no sequence levels in common.

Lastly, attempting to add gene ID's and feature names to these peaks with addGeneIDs() fails entirely, with the error Error: There is no feature column in annotatedPeak or annotatedPeak has size 0!

I hope this provides some useful context, thank you in advance for your help!

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jianhong avatar jianhong commented on August 19, 2024

Hi,

Thank you for reporting this. I patched the package to handle this error. Please try to update the package to development version and try it again. Let me know if you still have question.

Jianhong.

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jardplard avatar jardplard commented on August 19, 2024

Hi Jianhong,

Your patch worked great! Thank you so much for fixing it, you have saved a critical component of my analysis.

-Jared

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