Comments (8)
I hardcoded the imputation quality field in INFO as "INFO" while it could also be "R2".
I'll release a patch today.
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Ok, let me know if there is still an issue or if it goes smoothly, and in that case I'll release v0.17.4
..
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Will do, with use_info=TRUE it took about 2,5 days to finish.
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This should be fixed now, can you try to install the development version?
remotes::install_github("mcanouil/eggla")
PS: do not forget to provide the proper information for the imputation quality metrics by changing the default value for info_type
, i.e., info_type = "IMPUTE2 info score via 'bcftools +impute-info'"
, in your case it's something about "R2".
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Thanks, got the 0.17.4 and running the analysis now.
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I'll keep the issue open until you can confirmed it is fixed then.
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This worked! I quickly looked at the results, seems like everything else is OK I just need to add CALL_RATE.
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Great! I'll start the release process for v0.17.4.
I don't think the CALL_RATE is really needed though.
In theory, your data have been QCed, this implies a call rate threshold, thus the column will be between the threshold and one, which makes it not really useful for any postprocessing step.
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Related Issues (20)
- Replace slopes_dt with aucs_dt in outlier removal [run_eggla_lmm()]
- Inconsistent use of vep and vep_file in run_eggla_gwas() HOT 1
- Title of residual plots in run_eggla_lmm()
- New version of run_eggla_gwas not working HOT 16
- Increase of number of iterations for the EM algorithm `niterEM` HOT 5
- Currently in `egg_model` (and related), warnings are not necessarily captured
- Covariates and slopes HOT 6
- GWAS function output file to tab separated HOT 9
- Add AP and AR in addition to slopes and AUCs for GWAS
- Update knots from 2,8,12 to 1,8,12
- Check that all diagnostics figures/tables to the output of `run_eggla_lmm()` HOT 2
- Outlier plot legend getting mixed HOT 2
- All parameters correlations
- INFO_TYPE description given to genotyped SNPs HOT 5
- Incorrect parameter correlations HOT 4
- Release `eggla` `v1.0.0` HOT 5
- HWE_P in run_eggla_gwas() results inconsistent with analysis plan HOT 6
- N and EAF definition HOT 10
- Update default value for compute_apar function HOT 1
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