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bioruby-ucsc-api's Issues

travis-ci support for ucsc-api

Hi,

Since this is an important biogem,
please add bio-ucsc to travis-ci. Simply copy the .travis.yml file to the tree, and register the project with Travis, using your github acount. The next push will run the test system.

NoMemoryError: failed to allocate memory

I have been using this gem for some time with no problems. Suddenly it cannot allocate memory. I tried upgrading to 0.6.1 but it did not make a difference.

Rails 4.0.2
ruby 1.9.3p327 (2012-11-10 revision 37606) [i686-linux]

1.9.1 :003 > seqfile = Ucsc::File::Twobit.open("/home/assay/apps/assay/shared/bin/hg19/hg19.2bit")
NoMemoryError: failed to allocate memory
    from /home/assay/apps/assay/shared/bundle/ruby/1.9.1/gems/bio-ucsc-api-0.6.1/lib/bio-ucsc/file/twobit.rb:37:in `read'
    from /home/assay/apps/assay/shared/bundle/ruby/1.9.1/gems/bio-ucsc-api-0.6.1/lib/bio-ucsc/file/twobit.rb:37:in `block in load'
    from /home/assay/apps/assay/shared/bundle/ruby/1.9.1/gems/bio-ucsc-api-0.6.1/lib/bio-ucsc/file/twobit.rb:37:in `open'
    from /home/assay/apps/assay/shared/bundle/ruby/1.9.1/gems/bio-ucsc-api-0.6.1/lib/bio-ucsc/file/twobit.rb:37:in `load'
    from /home/assay/apps/assay/shared/bundle/ruby/1.9.1/gems/bio-ucsc-api-0.6.1/lib/bio-ucsc/file/twobit.rb:59:in `open'
    from (irb):3
    from /home/assay/apps/assay/shared/bundle/ruby/1.9.1/gems/railties-4.0.2/lib/rails/commands/console.rb:90:in `start'
    from /home/assay/apps/assay/shared/bundle/ruby/1.9.1/gems/railties-4.0.2/lib/rails/commands/console.rb:9:in `start'
    from /home/assay/apps/assay/shared/bundle/ruby/1.9.1/gems/railties-4.0.2/lib/rails/commands.rb:62:in `<top (required)>'
    from script/rails:6:in `require'
    from script/rails:6:in `<main>'

Can't install with Ruby 3.1

Hi.

The installation of mysql2 seems to fail.

At this time, it is Ruby 2.4. Is it similar? #6

Here is the error log.

Fetching activemodel-4.2.11.3.gem
Fetching tzinfo-1.2.9.gem
Fetching arel-6.0.4.gem
Fetching activesupport-4.2.11.3.gem
Fetching i18n-0.9.5.gem
Fetching safe_attributes-1.0.10.gem
Fetching activerecord-4.2.11.3.gem
Fetching mysql2-0.4.10.gem
Fetching bio-ucsc-api-0.6.5.gem
Fetching bio-genomic-interval-0.1.2.gem
Fetching activerecord-deprecated_finders-1.0.4.gem
Successfully installed arel-6.0.4
Successfully installed tzinfo-1.2.9
Successfully installed i18n-0.9.5
Successfully installed activesupport-4.2.11.3
Successfully installed activemodel-4.2.11.3
Successfully installed activerecord-4.2.11.3
Successfully installed safe_attributes-1.0.10
Building native extensions. This could take a while...
ERROR:  Error installing bio-ucsc-api:
	ERROR: Failed to build gem native extension.

    current directory: /home/kojix2/.rbenv/versions/3.1.0/lib/ruby/gems/3.1.0/gems/mysql2-0.4.10/ext/mysql2
/home/kojix2/.rbenv/versions/3.1.0/bin/ruby -I /home/kojix2/.rbenv/versions/3.1.0/lib/ruby/3.1.0 -r ./siteconf20220114-62428-kqri37.rb extconf.rb
checking for rb_absint_size()... yes
checking for rb_absint_singlebit_p()... yes
checking for ruby/thread.h... yes
checking for rb_thread_call_without_gvl() in ruby/thread.h... yes
checking for rb_thread_blocking_region()... no
checking for rb_wait_for_single_fd()... yes
checking for rb_hash_dup()... yes
checking for rb_intern3()... yes
checking for rb_big_cmp()... yes
*** extconf.rb failed ***
Could not create Makefile due to some reason, probably lack of necessary
libraries and/or headers.  Check the mkmf.log file for more details.  You may
need configuration options.

Provided configuration options:
	--with-opt-dir
	--without-opt-dir
	--with-opt-include
	--without-opt-include=${opt-dir}/include
	--with-opt-lib
	--without-opt-lib=${opt-dir}/lib
	--with-make-prog
	--without-make-prog
	--srcdir=.
	--curdir
	--ruby=/home/kojix2/.rbenv/versions/3.1.0/bin/$(RUBY_BASE_NAME)
	--with-ruby-dir
	--without-ruby-dir
	--with-ruby-include
	--without-ruby-include=${ruby-dir}/include
	--with-ruby-lib
	--without-ruby-lib=${ruby-dir}/lib
	--with-mysql-dir
	--without-mysql-dir
	--with-mysql-include
	--without-mysql-include=${mysql-dir}/include
	--with-mysql-lib
	--without-mysql-lib=${mysql-dir}/lib
	--with-mysql-config
	--without-mysql-config
	--with-mysqlclient-dir
	--without-mysqlclient-dir
	--with-mysqlclient-include
	--without-mysqlclient-include=${mysqlclient-dir}/include
	--with-mysqlclient-lib
	--without-mysqlclient-lib=${mysqlclient-dir}/lib
	--with-mysqlclientlib
	--without-mysqlclientlib
/home/kojix2/.rbenv/versions/3.1.0/lib/ruby/3.1.0/mkmf.rb:1086:in `block in find_library': undefined method `split' for nil:NilClass (NoMethodError)

    paths = paths.flat_map {|path| path.split(File::PATH_SEPARATOR)}
                                       ^^^^^^
	from /home/kojix2/.rbenv/versions/3.1.0/lib/ruby/3.1.0/mkmf.rb:1086:in `each'
	from /home/kojix2/.rbenv/versions/3.1.0/lib/ruby/3.1.0/mkmf.rb:1086:in `flat_map'
	from /home/kojix2/.rbenv/versions/3.1.0/lib/ruby/3.1.0/mkmf.rb:1086:in `find_library'
	from extconf.rb:95:in `<main>'

To see why this extension failed to compile, please check the mkmf.log which can be found here:

  /home/kojix2/.rbenv/versions/3.1.0/lib/ruby/gems/3.1.0/extensions/x86_64-linux/3.1.0/mysql2-0.4.10/mkmf.log

extconf failed, exit code 1

Gem files will remain installed in /home/kojix2/.rbenv/versions/3.1.0/lib/ruby/gems/3.1.0/gems/mysql2-0.4.10 for inspection.
Results logged to /home/kojix2/.rbenv/versions/3.1.0/lib/ruby/gems/3.1.0/extensions/x86_64-linux/3.1.0/mysql2-0.4.10/gem_make.out

TwoBit reader written in C extension

Hi, thanks for this awesome library!
I just wanted to let you know that I released bio-twobit yet another library to read 2bit files from ruby.

https://github.com/ruby-on-bioc/bio-twobit

This library is written in C extension and is expected to be fast. It may be used inside bioruby-ucsc-api if you like.

Feel free to create an issue on the project if anyone has feedback. Thanks!

2bit sequence retrieval broken for all Ns

If I try and retrieve a sequence that is all Ns by doing something like

puts hg19ref.find_by_interval("chr1:10-100")

or

puts hg19ref.subseq("chr1:10-100")

I get the following error:
ArgumentError: negative argument
from /Users/morriwork/.rvm/gems/ruby-1.9.3-p125@methAnalysis/gems/bio-ucsc-api-0.5.1/lib/bio-ucsc/file/twobit.rb:125:in *' from /Users/morriwork/.rvm/gems/ruby-1.9.3-p125@methAnalysis/gems/bio-ucsc-api-0.5.1/lib/bio-ucsc/file/twobit.rb:125:inblock in find_by_interval'
from /Users/morriwork/.rvm/gems/ruby-1.9.3-p125@methAnalysis/gems/bio-ucsc-api-0.5.1/lib/bio-ucsc/file/twobit.rb:117:in map' from /Users/morriwork/.rvm/gems/ruby-1.9.3-p125@methAnalysis/gems/bio-ucsc-api-0.5.1/lib/bio-ucsc/file/twobit.rb:117:infind_by_interval'
from (irb):9
from /Users/morriwork/.rvm/rubies/ruby-1.9.3-p125/bin/irb:16:in `

'

I am using ruby 1.9.3-p125 and I installed bioruby-ucsc-api from the gem.

bigBed / bigWig file formats

Many tables such as ncbiIncidentDB and wgEnsembleFooBar contains only a filename record pointing bigBed / bigWig files.

Some mechanism to support access to these files are required. Automatic download and caching is better.

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