V Source will not exceed 20.48V

If the error term in the PID calculation is negative, I believe the PID calculation falls apart. For example, if iLimit is 1.0 and iSource is 1.1, it calculates grossSetPoint = 0, fineSetPoint = 65533. Since for iSource = 0.9 you get grossSetPoint = 1 and fineSetPoint = 2, and for 0 error you get 0, there is clearly something wrong (the PID output should be a continuous function of the input). Looking at the code, it is clear there was no thought given to handling negative PID output. While it is possible the load may appear to operate correctly, I strongly suspect it is subject to overshoot and instability.

Connecting the Variable Load to a current limited source yields highly unexpected results.

The load shuts off entirely letting the source recover somewhat and then turns on again, cycling like that without equilibrium

Pin 15 and 16 for LCD backlight are unconnected, LCD backlight is inoperable.

Effectively means that any of the "x on black" LCDs are unusable.

I'm not entirely sure how to implement this, but it would be nice to be able to enable the load remotely rather than the buttons.

1. Are any jumpers labeled clearly by their function and possible settings? [NO]
   comment: The jumper between GND/GND-ISO is not labeled with its function

2. Have you verified that the BOM in Sparkle is accurate (also checking for PROD_ID, NAME, VALUE, PREFIX)? [NO]
   comment: There's an N-CHAN mosfet in the Eagle File's BOM but not in Sparkle

3. If there are any DRC errors, have they all been approved? [NO]
   comment: "Clearnance (polygons with same rank)" error for cap-sense pads.

4. Are there airwires after ratsnest? [YES]
   comment: 5V, 3.3V lines aren't routed. (not sure if correct version was uploaded)

5. Are the board dimensions on 0.05 inch or 0.01 inch grid? [NO]
   comment: Inches aren't specified in the measurements

6. Is the designer name included in tDocu? [NO]
   comment: You aren't in there as designer in tDocu

7. Are all jumpers labeled? [NO]
   comment: The GND/GND-ISO is also not labeled on the product

8. Are all labels lined up properly? [NO]
   comment: 1 and 4 denoting the layers can be removed

Small things:

1. Have you verified that the BOM in Sparkle is accurate (also checking for PROD_ID, NAME, VALUE, PREFIX)? [NO]
   comment: Mini USB needs to be updated.

2. Are all labels lined up properly? [NO]
   comment: I think I would like to see Load_ON, instead of just "ON" as your label for the LED indicator. It would make sense since you have Load_GND and Load_POS as labels already.

1. All of your schematic section labels are proportional font.

Note: This routing is top notch clip clop flip flop clap trap.