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*Cerna-Vargas J-P., *Gumerov V.M., Krell T., Zhulin I.B. (2023) Amine recognizing domain in diverse receptors from bacteria and archaea evolved from the universal amino acid sensor. PNAS, 120, e2305837120

Home Page: https://www.pnas.org/doi/epdf/10.1073/pnas.2305837120

License: MIT License

bioinformatics molecular-evolution motif receptor signal-transduction archaea bacteria

amine_motif's Introduction

Amine_motif

Data accompanying the paper on amine binding receptors

We defined the amine binding motif as follows:

[YWF] x (~20-34) [WYF] [WYF] x (~20-25) [MLIVAC] x [ST] x (~17-21) D

Multiple sequence alignments built using NCBI RefSeq sequences corresponding to the amine binding receptors are in the Alignment folder. The positions corresponding to the amine motif in the NCBI_RefSeq_Bacteria_Archaea.fa file are as follows:

[YWF] (534) x (~20-34) [WYF] [WYF] (713) x (~20-25) [MLIVAC] (896) x [ST] (905) x (~17-21) D (979)

The modeled structures of the amine receptors tested in the paper are in the Structures folder.

The bayesian phylogenetic tree and the multiple sequence alignment used are in the Phylogeny folder.

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