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jdwinkler-lanzatech avatar jdwinkler-lanzatech commented on May 26, 2024 1

Yes, this would be great-BLASTP (or DIAMOND) would be much faster than TBLASTN based on my experience.

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Waschina avatar Waschina commented on May 26, 2024

Hi Hongzhong,

in the current Version, gapseq supports only the genome input as nucleotide fasta sequence. But I agree, a protein fasta for the annotated proteins as alternative input would be a useful extension. I will mark this as a feature request, which we will address in an upcoming version.
Until then, you could use the coding sequences of your proteins in a nucleotide fasta as gapseq input as a workaround.

Best regards,
Silvio

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hongzhonglu avatar hongzhonglu commented on May 26, 2024

Thanks so much! Looking forward to the new functions.

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Waschina avatar Waschina commented on May 26, 2024

Yes, we actually have plans in those directions; specifically to employ DIAMOND.
But since this is not per se an issue in the workflow, would it be okay with you to convert this conversion to the discussion forum (a new feature in github)?

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jdwinkler-lanzatech avatar jdwinkler-lanzatech commented on May 26, 2024

Definitely!

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